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Euroinvestor Cockpit Social Media Investment Platform Wins Best New Financial Service Application in the Danish Internet Awards 2012 Synergistic benefit of anti-tumor therapy was observed when MVA-BN-HER2 immunotherapy was combined with PD-1 immune checkpoint blockade. Interestingly, PD-1 blockade stimulated a second immune checkpoint molecule, LAG-3, to be expressed on T cells. Combining MVA-BN-HER2 immunotherapy with dual PD-1 plus LAG-3 blockade resulted in comprehensive tumor regression in all mice treated with the triple combination therapy. In contrast, anti-PD-1 monotherapy triggered significantly higher levels of LAG-3 expression than MVA-BN-HER2 therapy but T cells remained confined to the tumor periphery. Combining MVA-BN-HER2 immunotherapy with PD-1 blockade resulted in high LAG-3 expression on CD8 T cells and CD8 T cell infiltration throughout the tumor and co-localization of CD4 and LAG-3 in patches of the tumor . Increased tumor infiltration by CD4 T cells was observed

Our Community Projects I had never been truly inspired by mechanical displays, and fountain jets left me cold – but the charms of natural, flowing water never ceased to stir my imagination. Ashley McKinney, a Communications Specialist for the institute, says that Bartram and his team published a study which estimated that 28 percent of the world’s population, or 1.8 billion people, had used unsafe water in 2010. That estimate was one billion people more than the estimate by UNICEF and the World Health Organization. As activists across the globe celebrate World Water Day on Saturday, UNC’s The Water Institute is working on campus and internationally to help make safe water and sanitation a reality for all people. Flowform® figure8 technology & the power of nature Given to plants, these minerals shorten the growing period, increase yield, reduce watering needs, increase drought and freeze resistance, plants produce more viable seeds, etc. Trials with chickens in Holland suggest

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